Prof. Dr. Fernando P. Cossío

6Fernando P. Cossío
 Fernando P. Cossío (1960, San Martin de Villafufre, Cantabria, Spain) studied chemistry at the Universidad de Zaragoza (Spain) and received his Ph. D. at the University of the Basque Country in 1986 (Prof. C. Palomo). After a postdoctoral stay at CNRS (Talence, France, Dr. J.-P. Picard), he joined the University of the Basque Country (UPV/EHU) as Profesor Titular (Associate Professor) in 1988 and Catedrático (Full Professor) in 2002. In 1993, after a short stay at UCLA in the laboratories of Prof. K. N. Houk he decided to combine theoretical and experimental organic chemistry to investigate the origins of selectivity in chemical reactions. The author of more than 160 peer reviewed papers and 7 patents, his research interests include pericyclic reactions (with special emphasis on thermal cycloadditions), C-C bond forming reactions, and medicinal chemistry.
From 1999 to 2001 he served at the UPV/EHU as the Dean of the Faculty of Chemistry. From 2001 to 2004 he was the Vice-Rector for Research and International Relations of this University. He is also a co-founder of Ikerchem, and Spin-off Company of the UPV/EHU focused on the design, chemical synthesis and development of novel chemical entities. Since 2009 he is the president of the Executive Committee of Ikerbasque, the Basque foundation for science.
Almirall Award of the Spanish Society of Medicinal Chemistry (1987).
Euskoiker Foundation Award (2005).
Dr. Antonio Esteve Foundation Award (2007).
Rivas Medal of The Organic Chemistry Section of the RSEQ (2012).
Selected Reviews and Papers: 
1. “Densely substituted unnatural L- and D-prolines as catalysts for highly enantioselective stereodivergent (3+2) cycloadditions and aldol reactions”; Conde, E.; Bello, D.; de Cózar, A.; Vázquez, M. A.; Cossío, F. P. Chem. Sci. 2012, 3, 1486-1491.
2. “An amine-catalyzed enantioselective [3+2] cycloaddition of azomethine ylides and α,β-unsaturated aldehydes: Applications and mechanistic implications” Reboredo, S.; Reyes, E.; Vicario, J. L.; Badía, D.; Carrillo, L.; de Cózar, .; Cossío, F. P. Chem Eur. J. 2012, in press.
3. “Hierarchical Selectivity in Fullerenes: Site, Regio, Diastereo and Enantio Control on the 1,3-Dipolar Cycloaddition to C70”; Maroto, E. E.; de Cózar, A.; Filippone, S.; Martín-Doménech, A.;  Suárez, M.; Cossío, F. P.; Martín, N. Angew. Chem. Int. Ed. 2011, 50, 6060-6064.
4. “Tandem [8+2] cycloaddition-2+6+2] dehydrogenation reactions involving imidazo[1,2a]pyridines and imidazo[1,2a]pyrimidines”; Aginagalde, M.; Vara, Y.; Arrieta, A.; Zangi, R.; Cebolla, V. L.; Delgado-Camón, A.; Cossío, F. P. J. Org. Chem. (Featured Article) 2010, 75, 2776-2784.
5. “Concerted and Stepwise Mechanisms in Metal-Free and Metal-Assisted [4+3] Cycloadditions Involving Allyl Cations”; Fernández, I.; Cossío, F. P.; Lledós, A.; Mascareñas, J. L. Chem. Eur. J. 2010, 16, 12147.
6. “Identification of (1H)-pyrroles as histone deacetylase inhibitors with antitumoral activity”: Zubia, A.; Ropero, S.; Otaegui, D.; Ballestar, E.; Fraga, M. F.; Boix-Cornet, M.; Berdasco, M.M Bartinez, A.; Coll-Mulet, L.; Gil, J.; Cossñio, F. P.; Esteller, M. Oncogene 2009, 28, 1477-1484.
7. “The Mechanism of the Ketene-Imine (Staudinger) Reaction in its Centennial: Still an Unsolved Problem?”; Cossío, F. P.; Arrieta, A.; Sierra, M. A. Acc. Chem. Res. 2008, 41,  925.
8. “Deeper Insight into the Mechanism of the Reaction of Photogenerated Metallaketenes and Imines”; Fernández, I.; Sierra, M. A.; Mancheño, M. J.; Gómez-Gallego, M.; Cossío, F. P. J. Am. Chem. Soc. 2008, 130, 13892.
9. “On the Stereodivergent Behavior Observed in the Staudinger Reaction between Methoxyketene and (E)-N-Benzylidenearyl Amines”; Banik, B. K.; Lecea, B.; Arrieta, A.; de Cózar, A.; Cossío, F. P. Angew. Chem. Int. Ed. 2008, 46, 3028.
10. “On the Affinity Regulation of the Metal-Ion-Dependent Adhesion Sites in Integrins”; San Sebastian, E.; Mercero, J. M.; Stote, R. H.; Dejaegere, A.; Cossío, F. P.; Lopez, X. J. Am. Chem. Soc. 2006, 128, 3554.